International Pyrin Workshop
November 16-17, 2023
International Pyrin Workshop
November 16-17, 2023
We are delighted to welcome you to the 1st International Pyrine Workshop held in Paris 16th and 17 of November 2023.
The spirit of this meeting is to bring together basic researchers, clinicians and patients to advance research in the field of pyrin - the protein involved in familial Mediterranean fever.
We are very fortunate to welcome the best research teams on the subject of auto-inflammatory diseases. We hope that the format of the meeting will enable new ideas to emerge that will ultimately improve knowledge of the disease and patient care.
This meeting was made possible thanks to the generosity of a patient who wished to bequeath part of his money to support medical and clinical research. We hope you share our enthusiasm for this innovative meeting format, which leaves considerable space for informal discussion and brainstorming.
Welcome to Paris !
GRATEAU Gilles
Sorbonne University, Paris, France Internal Medicine department, Tenon hospitalGRATEAU Gilles
Sorbonne University, Paris, France Internal Medicine department, Tenon hospital Professor of internal medicine and clinical immunology
GEORGIN-LAVIALLE Sophie
Sorbonne University, Paris, France Internal Medicine department, Tenon hospital Laboratory INSERM U_938, St Antoine hospitalGEORGIN-LAVIALLE Sophie
Sorbonne University, Paris, France Internal Medicine department, Tenon hospital Laboratory INSERM U_938, St Antoine hospital Professor of internal medicine and clinical immunology
HENTGEN Véronique
Versailles Hospital, French reference center for autoinflammatory diseases and amyloidosis (CEREMAIA)HENTGEN Véronique
Versailles Hospital, French reference center for autoinflammatory diseases and amyloidosis (CEREMAIA) Praticien hospitalier (MD)
DELON Jérôme
Inserm, Cochin Institute, Inserm U1016, CNRS UMR8104, Paris Cité UniversityDELON Jérôme
Inserm, Cochin Institute, Inserm U1016, CNRS UMR8104, Paris Cité University Inserm Researcher
HENRY Thomas
Inserm, CIRI Lyon, Inserm U1111, CNRS UMR5308, ENS Lyon, Univ. LyonHENRY Thomas
Inserm, CIRI Lyon, Inserm U1111, CNRS UMR5308, ENS Lyon, Univ. Lyon Director of Research (DR2)
JAMILLOUX Yvan
Croix-Rousse hospital, Lyon, FranceJAMILLOUX Yvan
Croix-Rousse hospital, Lyon, France MCU PH
09:45 : Opening and introduction
G Grateau, S Georgin-Lavialle, V Hentgen, T Henry, Y Jamilloux, J Delon
Moderation
S Georgin-Lavialle and G Grateau
10:00 - 10:20 : Pyrin inflammasome regulation-new activators
Flora Magnotti (CIRI, Lyon, France)
10:20 - 10:40 : Studying Familial Mediterranean Fever mechanisms in a genetic mouse model
Andy Wullaert (University of Antwerp., Belgium)
10:40 - 11:00 : Pyrin, FMF and neutrophils
Helmut Wittkowski (Muenster)
11:00 - 11:20 : Coffee break
Moderation
I. Aksentijevich & T. Henry
11:20 - 11:40 : Beyond pyrin: when other GTPases activate other inflammasomes
Laurent Boyer (INSERM, Nice University, France)
11:40 - 12:00 : CDC42 and pyrin
Jerome Delon (Cochin Institute, Paris, France)
12:00 - 12:40 : Phosphoprotein Phosphatase Activity Positively Regulates Oligomeric Pyrin to Trigger Inflammasome Assembly in Phagocytes
Jim Bliska (Darmouth Univ.ersity, USA)
12:40 - 13:00 : Pyrin inflammasome regulation-Differences mono-macro
Matthew Mangan (Institute of Innate Immunity, Bonn, Germany)
13:00 - 14:15 : lunch
14:20 - 17:35 : Moderation: I. Ben-Zvi & Y. Bilginier
Clinical session
14:15 - 14:40 : Adherence to Colchicine therapy
Véronique Hentgen (Versailles hospital, France)
14:40 - 15:20 : PAAND
Seth Masters (University of Melbourne, Australia)
15:20 - 16:00 : I692del
Ivona Aksentijevitch (NIH, USA)
16:00 - 16:30 : Coffee break
16:30 - 16:50 : Liver disease and FMF
Sophie Georgin-Lavialle (Tenon Hospital, Paris, France)
16:50 - 17:15 : Kidney transplantation for FMF
Hélène François (Bicêtre Hospital, Paris, France)
17:15 - 17:45 : On demand anakinra for FMF
Ilan Ben-Zvi (Tel HaShomern Israël)
17:45 - 18:05 : Fast diagnosis functional test for FMF
Yvan Jamilloux (Croix Rousse Hospital, Lyon, France)
18:00 - 19:00 : Round table
20:30 : Dinner
Modération: H. Lachmann & I. Kone-Paut
09:00 - 09:20 : Unmet needs in FMF: Patients point of view
Mr Belamich on the behalf of the French association of FMF (AFFMF)
09:20 - 09:50 : Unmet needs in FMF: Doctors point of view
Yelda Bilginer (Hacettepe University, Ankara, Turkey)
09:50 - 10:15 : Discussion together
10:15 - 11:00 : Coffee break and picture exposition
"How can researchers help clinicians and patients?
11:00 - 11:30 : DNA-bar code screen applied to MEFV variants"
Thomas Henry & Pauline Bronnec (CIRI, Lyon, France)
11:30 - 12:00 : Last minute hot and important new data communcations on FMF
- Guilaine Boursier (Montpellier, France)
- Helen Lachmann (London, UK)
- Special guest X
12:00 - 13:00 : How can we all collaborate on pyrin and FMF ? All Participants
Modération :
G Grateau, S Georgin-Lavialle, V Hentgen, T Henry , Y Jamilloux, J Delon
13:00 : Lunch box on demand
Saint Antoine Hospital
Espace Antoine MOÏANA
184 rue du Faubourg Saint-Antoine
75012 Paris - France
SAINT ANTOINE HOSPITAL
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